Herantis Pharma Plc is an innovative drug development company looking to break the boundaries of standard therapeutic approaches. Our regenerative medicine drug candidates include i. CDNF biological therapy that acts on the proteostatic mechanisms of disease for the treatment of Parkinson’s disease and other neurodegenerative diseases, and ii.

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CDNF and MANF are localized mainly to the lumen of endoplasmic reticulum The first-in-human study with CDNF, sponsored by Herantis Pharma Plc, was 

It was discovered by Professor Mart Saarma’s laboratory at the University of Helsinki and published in the leading scientific journal, Nature, in 2007. Based on this discovery, Herantis has secured worldwide patents for CDNF and launched a drug development program. Herantis Pharma Plc. Company release, Inside Information. 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc (“Herantis or the Company”), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis’ CDNF and xCDNF assets and to commence seeking 2020-02-25 Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Herantis Pharma Plc. Company release, Inside Information .

Herantis cdnf

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“We are delighted to support Herantis Pharma in their development programs in CDNF and latest generation xCDNF molecules. Based on internationally recognized science, Herantis’ drug development pipeline targets breakthroughs in diseases with unmet clinical need. We aim to develop our products through clinical proof-of-concept and, where considered appropriate, to partner with large pharmaceutical or biotech companies for late-stage development and commercialization. 2020-02-25 · Herantis Pharma Plc Company release, insider information 25 February 2020 at 9:00 AM Eastern European Time. Herantis Pharma Plc (“Herantis” or “Company”) announced today the topline results from the ongoing Phase 1-2 clinical trial examining Herantis’ proprietary neuroprotective factor and novel drug candidate, CDNF, in patients with Parkinson’s disease.

of Herantis' CDNF therapies for Parkinson's disease using Nanoform's proprietary biological nanoparticle technology. As a result, Nanoform 

Herantis Pharma Oyj: Herantiksen CDNF on turvallinen ja hyvin siedetty Vaiheen 1-2 tutkimuksessa 12 kuukauden hoidon jälkeen. Publicerad: 2020-08-27 (Cision) Herantis Pharma Oyj: Herantis Pharma Plc Announces CDNF Phase I-II Study Met Primary Endpoints of Safety and Tolerability at 12 months. Publicerad: 2020-08-27 (Cision) Herantis Pharma Oyj: NOTICE TO CONVENE HERANTIS PHARMA PLC'S ANNUAL GENERAL MEETING OF SHAREHOLDERS 23 Mar 2021 / Press release; Livestreamed Seminar Today - ABGSC Investor Day 9 March 9 Mar 2021 / Article; Herantis Pharma - H2’20 Report 3 Mar 2021 / Analys Herantis Pharma Plc announces topline results of Phase 1-2 CDNF trial Tue, Feb 25, 2020 08:00 CET. Topline analysis confirms positive safety and tolerability of CDNF in advanced-stage Parkinson’s disease patients, with encouraging biological responses as measured by PET imaging in some patients.

Herantis cdnf

Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease.

Herantis cdnf

En känd utmaning i läkemedelsvärlden vid behandling av hjärnan är att ta sig förbi blod-hjärnbarriären. Herantis Pharma är noterat på Nasdaq First North i både Stockholm och Helsingfors. CDNF, or Cerebral Dopamine Neurotrophic Factor, is an endoplasmic reticulum located and secreted protein with neuroprotective and neurorestorative properties, patented worldwide by Herantis. Encouraged by strong preclinical proof-of-concept Herantis is launching a first-in-human, randomized Phase 1-2 clinical study with CDNF for the treatment of Parkinson's disease in 1H/2017. Herantis Pharma Oyj (“Herantis” tai “Yhtiö”), innovatiivinen kliinisen vaiheen lääkekehitysyhtiö, joka kehittää uusia sairauden kulkuun vaikuttavia regeneratiivisia hoitoja, tiedotti tänään yhtiön hallituksen päättäneen keskittää Herantiksen resurssit yhtiön CDNF- ja xCDNF-ohjelmiin ja aloittaa lisensointikumppanin etsimisen Lymfactinin kliiniselle kehitysohjelmalle CDNF – a biological protein – is Herantis’ lead program and a clinical stage asset; and xCDNF – a synthetic peptide version of CDNF – is Herantis’ follow-on program. Both CDNF and xCDNF have, via their multimodal mechanism of action, the potential improves neuronal survival and to stop the progression of Parkinson’s and other About CDNF.

Herantis cdnf

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Herantis Pharma keskittyy CDNF- ja xCDNF-ohjelmiin Herantis Pharma Oyj (“Herantis” tai “Yhtiö”),. Kuten aikaisemmassa Yhtiön tiedotteessa 2.3.2021 kerrottiin, Lymfactinin Webinaariin voi rekisteröityä alle olevasta linkistä..

Herantis Pharma Plc. Company release, Inside Information. 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc (“Herantis or the Company”), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis’ CDNF and xCDNF assets and to commence seeking Herantis Pharma Announces an Oral Presentation and a Poster Presentation related to First-in-Man CDNF Clinical Trial at AD/PD™ Virtual Conference Read more Proposals of the Shareholders’ Nomination Committee to Herantis Pharma Plc’s Annual General Meeting 2021 Herantis Pharma has announced that its novel drug candidate, Cerebral Dopamine Neurotrophic Factor (CDNF) for the treatment of Parkinson’s disease (PD), has successfully achieved its primary endpoint of safety and tolerability in a 12 month Phase I-II study in patients with moderate disease. Intracerebral delivery abandonedMore patient friendly methods to be exploredA fresh start with an accelerated development trajectoryIntracerebral delivery deeme Herantis Pharma Plc. Company release, Inside Information 29 March 2021 at 9:00 PM EET. Herantis Pharma Plc ("Herantis or the Company"), an innovative clinical stage biotech company pioneering new disease modifying and regenerative therapies, today announced that the Board of Directors has decided to focus all company resources on Herantis' CDNF and xCDNF assets and to commence seeking out “ CDNF is now one of a few clinical stage assets in development with the potential for disease modification of Parkinson’s Disease. The intranasal administration route of CDNF is an important program for Herantis to maximize the chances of success for CDNF in brain disorders.
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17 Dec 2020 It could “revolutionise Parkinson's disease treatment”, said Henri Huttunen, chief scientific officer at Herantis Pharma. Explaining the background 

Subject to finalizing definitive agreements, Nanoform will in this partnership carry out, for compensation on standard commercial terms, two Proof of Concept studies on Herantis' CDNF and xCDNF Nanoform is committed to supporting Herantis in the development of these programs and has undertaken to invest, subject to certain customary conditions, 1,600,000 euros in a planned immediate directed share issue by Herantis. “We are delighted to support Herantis Pharma in their development programs in CDNF and latest generation xCDNF molecules.